Personally I've all but dumped Microsoft Office in favour of Google Apps. Sure, Office has a lot more and can do a lot more, but for my needs Google has it covered and "my stuff" is available wherever I happen to be, from the multi-PC environment at home to out and about with my laptop/phone whatever. I can still work effectively.
I started back when Google first started their online spreadsheets and haven' looked back since. Have pretty much converted my partner too and a few others. Online collaboration with docs and spreadsheets really works for us.
The only thing I still use is MS Access as it's a back-end for a few web sites. Who knows, maybe that will change in the near future too.
We've got a lot to thank Microsoft for, but Google's stuff is looking shiny, new and exciting not to mention free.
People will vote with their mouse and wallet.