I use scrapebox for FINDING potential link partners, but I don't use it at all for posting in blogs (or doing any posting).
It seems like it has gotten harder to use because you need to really use up a lot of proxy servers, and they seem to be getting harder and harder to find free ones.
Never used SE Nuke before. I know someone who has paid for blasts with senuke in the past and they say that strategy is pretty much ineffective now. But that's one person's opinion.
There are definitely sites ranking out there that APPEAR to have been blasted. Whether those are the links that actually propelled the site to the top of the SERPs or not is debatable.