victor - 11:32 pm on Feb 26, 2006 (gmt 0)

Accesskeys are a bit like the bad old days of DOS applications -- no standard key shortcuts at all: you ran the risk of hitting F1 in one application for help, and having it exit without saving, or starting to print.

If you do offer accesskeys, best to not make for even more non-standard combinations, so uk UK.gov recommendations are a good start:

[cabinetoffice.gov.uk...]

How do visitors know you are using them? You need to tell them. As the UK.gov page says:
When this navigational system is made available, it is important to inform your website users, as soon as they enter.

It is good to offer accesskeys -- they are the only or best way around sites for some visitors.