bill - 11:02 am on Nov 1, 2008 (gmt 0)

I run the 64-bit Vista Business version on one machine, and the lack of 64-bit hardware drivers has been the biggest issue I've faced. I run a VMware virtual machine with 32-bit XP in it to work around this. An old scanner and several printers in my office simply don't have the drivers.

64-bit XP must be a real joy...