I've embedded adsense with my press release distribution website. The website is just 4 months old and which is doing great. I'm getting around 300 page views a day. The adsense units I was using was two 160X600 units in both sides (top left and top right) when I started the service. But it could give me clicks very rarely. Then people adviced me to put ads inside the content so I've placed a text link on top of the content just below the title and the revenue began to increase and reached 2-4 clicks and 1.5$ minimum a day.
But when I searched on adsense support forum every one is talking about link units. So I removed the right side ad unit and put a link unit just below the header, yesterday. Though the revenue is still 2$ per day. The number of clicks had increased. I've got 6 clicks yesterday from the link unit.
[edited by: martinibuster at 7:00 am (utc) on Jun 15, 2010] [edit reason] See TOS [webmasterworld.com] [/edit]
Still early days yet to establish what is going to work best for your traffic.
160X600 on the left sidebar converts well for me. I have a 250x250 unit within the articles that floats to the right, although I get less clicks it actually earns more. I also use the text link unit between the main top nav and title of the article which converts well.
In some articles, not all, I use a unit at the bottom but they dont convert too well for me. Not forgetting, I also use Google Custom Search boxes, one at the top right of the site and one at the very bottom of each article - Google CSE converts really well for me but it also gives me an insight what people are looking for on the site.