A lot of clinics are logically grouped together to a large clinic center which is planning a new "website": Taking into account best practises and regarding now all the possible penalties and updates such as Panda, Penguin etc. would a subdomain concept be a better solution than establishing multiple single domains? (in both cases interlinking and managing the whole in the right way; Bing and other SEs dont matter)
Very interested in your thoughts about pros and cons.
I wouldn't use subdomains unless each clinic can really stand on its own as a kind of self-sufficient website. However, this decision today is not that big a deal. In the past, there were ranking advantages, especially when it came to reputation management. Today - not so much. So the decision comes down to ease of admin for you, IMO.