I removed AdSense from all pages of a site of mine except one page, which is one of the top 2 pages in terms of page views. Let's refer to my CTR before that change as 100. It's now 700 and I don't expect to get a fraudulent activity notice.
BTW, due to how impressions and clicks are calculated the CTR in the AdSense reports is either misleading or flat out incorrect depending on your perception. That's because here's what each measures:
Impression - each time a block of ads are displayed, regardless of whether it's a paid or unpaid (public service announcement) ad
Click - each time a paid ad is clicked
This is not simply my opinion; it's a fact based on testing on a site which displayed a very high percentage of unpaid PSA ads due to Google incorrectly categorizing many of the pages as "negative content" (apparently to deal with adult content pages, though the site deals with crime).
In my case over 90% of the impressions are for PSAs. So if all pages serve AdSense ads the CTR is extremely low. If I limit AdSense code to one or two specific pages it's magnitudes> higher.
Let's take a hypothetical day.
Paid ads served: 1,000
Unpaid ads served: 9,000
Paid clicks: 90
Unpaid clicks: unable to determine
Google calls that a CTR of 0.9% (90/(1,000+9,000)).
It's really 90+Unknown/(1,000+9,000)).
But what I care about is the paid CTR of 9.0% (90/1,000).
In my opinion, Google should redo their reports as follows:
Paid Impressions: 1,000
Unpaid Impressions: 9,000
Paid clicks: 90
Paid CTR: 9.0%
They could also include unpaid clicks, though they'd have to call an internal Google page first for those ads instead of calling the destination URL directly like they do now.